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Research Protocols

Cell Signal Protocol

Lyophilised Powder  ·  For Research Use Only

Original price was: £94.98.Current price is: £84.99.
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Royal Mail Tracked 24
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Free shipping over £100
For research use only — not for human or veterinary use

The Cell Signal Protocol is a two-compound research bundle combining MOTS-c 40mg and 5-Amino-1MQ 10mg — selected for their complementary roles in mitochondrial function and metabolic signalling research.

MOTS-c 40mg MOTS-c is a mitochondrial-derived peptide encoded within the 12S rRNA gene of mitochondrial DNA. It is studied for its role in AMPK pathway activation, mitochondrial-nuclear communication, and cellular stress response. Research has explored its influence on glucose metabolism, insulin sensitivity, and skeletal muscle function. MOTS-c levels are known to decline with age, making it a subject of interest in longevity and metabolic research.

5-Amino-1MQ 10mg 5-Amino-1MQ is a small molecule inhibitor of nicotinamide N-methyltransferase (NNMT), studied for its role in NAD⁺ pathway modulation and cellular energy metabolism. Research has investigated its effects on lipid metabolism, mitochondrial biogenesis, and adipogenesis inhibition.

Why this combination? Both compounds target overlapping aspects of mitochondrial and metabolic signalling — MOTS-c via direct AMPK activation and mitochondrial-nuclear crosstalk, 5-Amino-1MQ via upstream NAD⁺ regulation. This makes them a frequently paired combination in structured mitochondrial function research.

All Polygon Peptides products are third-party tested via Janoshik with certificates of analysis available on each product page. Supplied as lyophilised powder for research use only. Not intended for human or veterinary use.

Before reconstitution: store at room temperature away from direct light. Stable at ambient temperatures prior to reconstitution.

Reconstitution: add bacteriostatic water slowly to the vial using a syringe. Swirl gently — do not shake. Use our Reconstitution Calculator for the correct volume.

After reconstitution: refrigerate at 2–8 °C. Avoid freeze-thaw cycles. Use within 28 days.

Dispatched via Royal Mail Tracked 24 in discreet packaging. Orders before 1pm GMT on working days ship same day.

Flat rate £4.99 shipping. Free on orders over £100. See our Shipping Policy.

Supplied strictly for laboratory and scientific research only. Not for human consumption, medical treatment, or veterinary use. Not evaluated by the MHRA or FDA.

By purchasing you confirm you are 18+, have appropriate facilities to handle research chemicals, and accept responsibility for legal compliance in your jurisdiction.

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